CCR2 drives neutrophil infiltration and elicits tissue damage in remote organs during sepsis
نویسندگان
چکیده
منابع مشابه
PAF and CD18 mediate neutrophil infiltration in upper gastrointestinal tract during intra-abdominal sepsis.
Neutrophil infiltration is a critical event in the development of multiple organ failure during sepsis. We hypothesized that platelet-activating factor (PAF) release contributes to neutrophil infiltration in the gastrointestinal tract during sepsis. In the first experiments we administered exogenous PAF (1.56, 6.25, 25, and 100 ng ⋅ kg-1 ⋅ min-1for 30 min) to urethan-anesthetized Sprague-Dawley...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2010
ISSN: 1364-8535
DOI: 10.1186/cc9126